This paper focuses on the nature of contemporary occurrences and management of cholera epidemics, and representations of the disease in various spaces: politico-administrative, scientific, clinical and the affected communities. In each of these spaces, we have examined the processes and practices of normalising a crisis produced by the epidemic potential of the disease. We also examine how experimentation and bio-medical research for developing new vaccines or new drugs, far from being perceived as instances of bio-medical power, come to be seen as an important resource by the community.