The development of a history of science, technology, environment and medicine (HISTEM) in south Asia has not merely to draw on different disciplines, but also has to shape its concerns from unique and divergent regional traditions and histories that prevail in the region. The south Asian techno-scientific tradition has largely been a syncretic one, evolving as a result of socio-politico and cultural interactions through the ages; the colonial experience too played its part. The appeal of HISTEM is therefore wider, it belongs to the mainstream of social and cultural debates in history.